Latex Particle for In-Vitro Diagnostics

Latex Particle for In-Vitro Diagnostics Hi・spheres™

Hi・spheres™ is a latex particle for in vitro diagnostics manufactured by soap-free polymerization.Latex particles manufactured by this technology do not use any surfactants in the process, and are superior in adsorption and binding of biomolecules such as antibodies.Special modification of the particle surface prevents agglomeration of latex particles during the sensitization process and ensures smooth redispersion in ultrasonic dispersion after centrifugal separation.

feature

Excellent adsorption and binding of biological substances
Prevents agglomeration of latex particles in the sensitization process
Good redispersibility by ultrasonic dispersion
Two types; Physical Adsorption type, Chemical Bonding type
Chemical bonding type is selectable from three levels of carboxy group content
(Almost identical grain size, Low is recommended for initial study)
Controlled grain size for each lot (fig.1)
Advance samples are available
Standard antibody sensitivity protocols to support users

Hi・Spheres™ Product list

Particle size Solids content	Plain Product Particle size (example nm)	COOH_Low Product Particle size (example nm) -COOH (example μmol/g)	COOH_Middle Product Particle size (example nm) -COOH (example μmol/g)	COOH_High Product Particle size (example nm) -COOH (example μmol/g)
350±20 nm 10.0-10.2 %	Hi・Spheres™ P350 358 nm	Hi・Spheres™ C350_Low 344 nm 36 μmol/g	Hi・Spheres™ C350_Middle 348 nm 46 μmol/g	Hi・Spheres™ C350_High 359 nm 53 μmol/g
300±20 nm 10.0-10.2 %	Hi・Spheres™ P300 314 nm	Hi・Spheres™ C300_Low 302 nm 42 μmol/g	Hi・Spheres™ C300_Middle 303 nm 52 μmol/g	Hi・Spheres™ C300_High 301 nm 61μmol/g
250±20 nm 10.0-10.2 %	Hi・Spheres™ P250 259 nm	Hi・Spheres™ C250_Low 251 nm 50 μmol/g	Hi・Spheres™ C250_Middle 253 nm 62 μmol/g	Hi・Spheres™ C250_High 250 nm 70 μmol/g
200±20 nm 10.0-10.2 %	Hi・Spheres™ P200 212 nm	Hi・Spheres™ C200_Low 206 nm 61 μmol/g	Hi・Spheres™ C200_Middle 200 nm 77 μmol/g	Hi・Spheres™ C200_High 202 nm 86 μmol/g
150±20 nm 10.0-10.2 %	Hi・Spheres™ P150 159 nm	Hi・Spheres™ C150_Low 152 nm 84μmol/g	Hi・Spheres™ C150_Middle 155 nm 103 μmol/g	Hi・Spheres™ C150_High 152 nm 114 μmol/g
100±15 nm 5.0-5.2 %	Hi・Spheres™ P100 108 nm	Hi・Spheres™ C100_Low 98 nm 162 μmol/g	Hi・Spheres™ C100_Middle 99 nm 210 μmol/g	Hi・Spheres™ C100_High 97 nm 247 μmol/g
70±10 nm 5.0-5.2 %	Hi・Spheres™ P70 75 nm	Hi・Spheres™ C70_Low 65 nm 257 μmol/g	Hi・Spheres™ C70_Middle 65 nm 337 μmol/g	Hi・Spheres™ C70_High 65 nm 415 μmol/g

Fluorescent particles(Europium Particle)

Made of carboxylic acid-modified particles colored with europium chelate, these particles are specifically designed for immunochromatography.
Europium chelate particles have an extremely high Stokes shift, which helps prevent nonspecific fluorescence interference.

feature

No loss of dye to water or buffer solution
uniform-sized polystyrene latex
High dispersibility based on particle design

Specification

Excitation wavelength: 330nm /
Fluorescence wavelength: 615nm
Functional group: Carboxylic acid
Material: Polystyrene
Fluorescent Material: Europium
Additive: 0.05wt% sodium azide

Europium Latex　〔Chemical bonding type〕

Code NO.	Particle size μm	Example μm	-COOH μmol/g	Example μmol/g	Solids Content %
CBN-100 plus_Eu	0.080-0.130	0.105	110-170	145	1.0-1.1
CBN-200 plus_Eu	0.170-0.230	0.190	60-90	73	1.0-1.1
CBN-300 plus_Eu	0.280-0.320	0.302	30-70	47	1.0-1.1

■ Size: 1mL / 4mL / 100mL / Others are negotiable

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Latex Particle for In-Vitro Diagnostics

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Specification

Europium Latex 〔Chemical bonding type〕

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Europium Latex　〔Chemical bonding type〕